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Grape Seed Extract is one of the most powerful antioxidants found. Grape Seed Extract benefits include the uncanny ability to strengthen blood vessel walls within hours after taking it. Our Grape Seed Extract is blended with grape skin and red wine extract for maximum antioxidant benefits.
Grape seed extract is a powerful antioxidant made by extracting substances called oligomeric proanthocyanidins from the seeds and skin of grapes. As an antioxidant, grape seed extract works as a free radical scavenger. It binds to the unpaired electrons of free radicals, which are byproducts of oxygen reactions in the body.
Free radicals are the result of metabolic
reactions that occur in the body every day as a result of exercise, smoking,
pollution and other factors. While a stable oxygen atom has eight electrons, a
free radical has only seven. Left alone, these unstable molecules are capable of
causing significant damage to the body as they seek another electron for
stability. Free radicals accelerate the aging process and contribute to the
development of cancer cells. In order to keep free radicals from causing
excessive damage to body tissue, antioxidants are needed to provide the electron
needed to stabilize them.
Many substances, including phytochemicals (plant extracts) like grape seed, as
well as some vitamins and minerals, have antioxidant properties. Grape seed
extract is thought to be one of the most powerful of these antioxidants,
considered to be 20 times more powerful than vitamin C and 50 times more
powerful than vitamin E. It belongs to a class of antioxidant phytochemicals
known as bioflavonoids, which are found in fruits, vegetables, grains and seeds.
In Europe, grape seed extract is prescribed to treat cardiovascular disease, varicose veins, water retention, and arthritis. Because it is used pharmacologically, it has undergone extensive testing. Numerous clinical studies support claims that grape seed extract has a variety of positive effects on health. For example, it is capable of crossing the blood-brain barrier so it can act on the brain and spinal nerves, protecting the nervous system from free radical damage. It can also bind to collagen fibers, increasing muscle flexibility and elasticity of tendons and ligaments.
A related benefit is the ability of grape seed extract to fight high blood pressure by acting as a muscle relaxant in blood vessels. In addition, it prevents the oxidation of LDL cholesterol, a key factor in the development of cardiovascular disease. Grape seed extract can also prevent blood platelets from sticking together and forming clots that can cause strokes.
Grape seed extract is available in tablet, liquid and capsule form. A quality product should be standardized to contain at least 92% proanthocyanidins. It is generally taken in daily doses of 100 mg for general antioxidant use and cancer-prevention.
Smokers can take up to three times that amount. For specific ailments, the recommended dosage of grape seed extract is 100 mg three times a day. Grape seed extract can be taken any time of day, but it should be taken at the same time every day. To be of benefit, it must be taken on a regular basis to maintain blood levels of proanthocyanidins. Grape seed extract is extremely safe, with no significant reactions or toxicity reported from supplement use.
Source: http://vitamins.ultimatefatburner.com/grape-seed-extract.html
A concerted study by scientific researchers into the benefits of Grape Seed Extract began in earnest in the early 1990s in an attempt to resolve the so-called French Paradox. After the regimented Pritikin-style diets of the 1980s, it came as a surprise to researchers in the area of cardiovascular health to find that the typical French diet, consisting of a high proportion of saturated fats, actually resulted in lower rates of heart disease than those of other Western countries.
This paradox was attributed to the presence of red wine in the typical French diet, and subsequent studies isolated powerful antioxidants, named oligomeric proanthocyanidins (or OPCs), in red wine grape seeds.
Earlier studies of OPCs date back as far as 1951, when researchers from the University of Bordeaux in France extracted OPCs from both pine bark needles and grape seeds. The evidence suggests that the OPCs present in Grape Seed Extract are up to 20 times more potent than Vitamin C and 50 times stronger than Vitamin E. In addition, Grape Seed Extract has been shown to remain in the body for up to three days, significantly longer than the more commonly used antioxidants, Vitamins C and E.
Documented studies suggest that Grape Seed Extract works by strengthening collagen in blood vessels, leading to increased blood flow throughout the body. Thus, the compound is useful for the prevention and treatment of vascular disorders such as arteriosclerosis, chronic venous insufficiency (including swelling, pooling of blood, varicose veins, and hemorrhoids), macular degeneration, periodontal disease, circulatory disorders associated with diabetes, and erectile problems.
Research also indicates that the antioxidants present in Grape Seed Extract are multifunctional in the way they scavenge potentially damaging free radicals in the body. While Vitamin C protects against water-soluble oxidants, and Vitamin E neutralizes fat-soluble oxidants, the OPCs found in Grape Seed Extract defend against both.
At present, animal evidence suggests that OPCs can slow and even reverse clogging of the arteries. Human studies point to the efficacy of Grape Seed Extract in the treatment of edema (swelling after surgery), and it may possibly assist in dealing with high blood pressure, lupus, and cirrhosis of the liver.
In all, over 90 research publications have detailed the health benefits of Grape Seed Extract, including articles in Toxicology, The Journal of Medicine, Fitoperia, and The Journal of Agricultural Food Chemistry. The latter journal article outlines the benefits of Grape Seed Extract on Alzheimer's and other neurodegenerative disorders. Researchers in the study of ADD and ADHD have noted significant improvement in the behavior of children suffering from these disorders. The ability of Grape Seed Extract to transect the blood-brain barrier means that Grape Seed Extract has the potential to impact significantly on psychoneurological health. Further research will allow scientists to fully understand the already considerable benefits of Grape Seed Extract.
Source: http://www.vitabase.com/articles/grapeseedresearch.asp
One of the Most Potent Antioxidants Yet Discovered!
Grape Seed Extract is one of nature's unique antioxidants. Help your body fight free radicals with all natural Activin™, a high-potency Grape Seed Extract rich in biologically active flavonoids - one of the unique antioxidants yet discovered. Antioxidants can help prevent the cellular damage caused by free radicals. Activin™ products are produced using the environmentally safe Acti-Pure™ method. Instead of using toxic solvents and/or harsh chemicals, Acti-Pure™ utilizes a high-tech water and ethanol extraction process which preserves the natural balance of biologically active flavonoids found in Grape Seed Extract. Grape seed extract is derived from the small seeds (and occasionally the skins) of red grapes--the same kind that are pressed to make wine.
Used extensively in Europe, Grape Seed Extract is rich in flavonoids, phytochemicals that have antioxidant properties some consider even greater than the old standbys vitamin C and vitamin E. Antioxidants are believed to prevent and control numerous ailments by safeguarding cells against the ravages of unstable oxygen molecules called free radicals. The most valuable flavonoids in Grape Seed Extract are procyanidolic oligomers (also known as proanthocyanidins), commonly called PCOs. Beyond their antioxidant powers, PCOs are thought to improve blood circulation and help strengthen blood vessels. These actions benefit people with heart disease and cancer. As an ingredient in facial creams, the extract may help maintain skin elasticity; many European skin creams feature grape seed extract for this purpose.* For additional product information, click here.Grape Seed Extract Benefits:
Prevent heart disease
Minimize fibromylagia damage
Deter cancer
Fight skin diseases such as psoriasis and eczema.
Slow progression of macular degeneration and cataracts
Lessen allergy symptoms
Ease eye strain
Source: http://healthproducts-usa.com/n_grape_seed.htm
Grape Seed Extract:
Scientists have discovered that certain nutrients can help you look younger and feel healthier.
An important nutrient in the quest for anti-aging, long term health and well-being is Grape Seed Extract.
Grape Seed Extract is known as a powerful antioxidant.
Antioxidants help protect the body from damage from free radicals.
The antioxidant capacity of grape seed extract comes from proanthocyanidins (oligomeric proanthocyanidins) (OPCs).
Scientific studies have shown that proanthocyanidins antioxidant power is 20 times stronger than Vitamin C and 50 times stronger than Vitamin E.
Extensive research suggests that the proanthocyanidins found in Grape Seed Extract may be beneficial in many areas of health due to their antioxidant effect.
More Research Studies
Proanthocyanidins have been used for decades in Europe to improve circulation, reduce edema and varicose veins.
In a double blind study of 50 patients with chronic venous insufficiency, Grape Seed Extract alleviated symptoms of this circulatory disorder.
Another study of 25 patients with high blood pressure or diabetes who were given 150 milligrams of proanthocyanidins per day showed a significant increase in capillary strength as compared to the placebo group.
A double blind, placebo-controlled study involving 92 patients with peripheral venous insufficiency showed that proanthocyanidins substantially reduced pain, night time cramps and subjective edema.
Declining vision is common with aging. According to a recent clinical study; proanthocyanidins may play a role in improving vision.
In a research study, 100 people who were free of eye defect and eye disease were given 200 milligrams of proanthocyanidins daily for four weeks.
The subjects were tested for their resistance to blinding and for their ability to see in dim light. 98 out of 100 test subjects showed an improvement in vision as a result of supplementing with proanthocyanidins (grape seed extract).
Proanthocyanidin, the active ingredient of grape seed extract has been proven to be 20 times more potent than Vitamin C and 50 times more potent than Vitamin E as an antioxidant!
Science News magazine, the weekly news magazine of Science, published the findings of Dr. Ho (Tufts University, Medford, MA) on February 22, 1997.
Dr. Ho found a direct link between free radicals and prostate cancer. This type of cancer is the second leading cause of cancer deaths in men.
The article in Science News goes on to say: "New findings in this area suggest that dietary and other antioxidant therapies may hold great promise for curbing this scourge."
The article states further: "Several studies have found that men taking vitamin E, a potent antioxidant, are far less likely to develop prostate cancer than men who don't supplement their diets with the vitamin." Remember that Grape Seed Extract is 50 times more potent than vitamin E as an antioxidant!
Benefits of Grape Seed Extract
Grape Seed Extract is good for:
Living longer and healthier
Source: http://www.womens-health-symmetry.com/grape-seed-extract.html
Grape Seed Extract Benefits
Anti-Inflammatory
One of the initial benefits of PCO noticed by physicians as early as 1950 was
its anti-inflammatory action. This is partly produced by the antioxidant effect,
and also by hindering the release and synthesis of compounds that encourage
inflammation, such as histamine and prostaglandins. PCO selectively attaches to
the connective tissue of joints, helping prevent swelling, healing damaged
tissue, and reducing pain.
Anti-Histamine
The anti-histamine effect of PCO is mediated by an inhibiting effect on the
enzyme histidine decarboxylase, which is responsible for the production of
histamine. This is enhanced by the ability of PCO to block hyaluronidase, the
enzyme that aids the release of histamine into body tissues.
Anti-Allergic
This action is connected with the antihistamine effect, in addition to the
ability of PCO to strengthen certain cell membranes that contain the allergic
chemicals, and as a result avoiding over-reaction or hypersensitivity to pollens
and food allergens. Many allergy sufferers have reported considerable relief
using grape seed extract.
Anti-Ulcer
Ulcers provoked or aggravated by stress are related to undue secretion of
histamine in the stomach lining. PCOs help heal ulcers by reducing the discharge
of histamine and by attaching to and protecting connective tissue in mucous
membranes.
Cardiovascular Disease
Investigational research has discovered that oxidation of LDL cholesterol is a
vital factor that leads to hardening of the arteries and heart disease. The
antioxidant effect of Vitamin E has been demonstrated to be a powerful inhibitor
of this oxidation process - and PCO is known to be 50 times more potent than
vitamin E. It has also been shown that PCO helps to inhibit the stickiness of
blood platelets that can lead to strokes and blood clots. Patients who take PCO
in the form of grape seed extract have reported lowered blood pressure and
cholesterol levels.
Cancer Prevention
Experimental evidence has been available for some time demonstrating that
antioxidants can significantly reduce the occurrence of all forms of cancer. One
study has shown that the risk of developing cancer is 11.4 times greater for
those with depleted levels of the antioxidants vitamin E and selenium. PCO is a
more potent antioxidant than these, and also protects cellular DNA from the
oxidative damage and cell mutationsthat can lead to cancer.
Teeth and Gums
Dentists and their patients have testified that PCO gives healing and preventive
benefits to the teeth and gums. These are thought to be through its
anti-inflammatory action, free radical quenching, and protection of connective
tissue.
Eyes
Clinical studies have demonstrated that antioxidants can stop the progress of
cataracts. PCO is strongly attracted to the portion of the retina that is
responsible for visual perception. It checks free radical damage and strengthens
the collagen structures of the retina. In clinical trials of patients with a
variety of types of retinal disease, all those given PCO showed considerable
improvement following therapy. Physicians monitoring the effects of PCO have
noted that it has also helped in the prevention and treatment of glaucoma.
Skin Care
Products containing PCO can help protect the skin from the ultraviolet radiation
damage that results in wrinkles and skin cancer. Since it stabilizes collagen
and elastin, PCO can help enhance the elasticity and youthfulness of the skin.
Individuals taking grape seed extract PCO have observed that it helps tone their
skin and reduce stretch marks, cellulite, and scars. It is thought that
cellulite may be a sign of bioflavanoid shortage.
Nervous System
Some doctors have reported that patients with multiple sclerosis (MS) have shown
improvement while taking PCO. MS is a condition in which the myelin sheath that
surrounds the nerves becomes progressively hardened and destroyed. Research
indicates that MS may be caused by an allergic or autoimmune reaction. Much
research has shown that activity levels of the antioxidant enzyme glutathione
peroxidase are significantly reduced in patients with MS.
The capacity of PCO to reduce the progressive symptoms of MS may be due to its
potent antioxidant and anti-allergic qualities. Also, PCO is able to go across
the blood-brain barrier, where it may protect the brain's nervous tissue from
oxidation. This may explain why patients taking PCO often report better mental
clarity.
Lungs
It has also been found that asthma and emphysema benefit from the use of PCO.
Asthma is mainly caused by an allergic reaction in the bronchial tubes that
results in bronchial constriction and an excessive amount of mucous excretion.
Because of its ability to inhibit histamine and other chemicals that cause
inflammation, PCO is effective in treating asthma.
Grape seed extract PCO has also been found to reduce the coughing, wheezing,
weakness, mucous and recurring respiratory infections usually associated with
emphysema. PCO appears to reduce the damage and inflammation to the air sacs of
emphysema patients.
Other possible benefits
Anecdotal reports from people using grape seed extract credit it with helping
the following conditions: Allergies; arthritis; asthma; blocked coronary
arteries; poor circulation; high cholesterol; diabetes (insulin dependence);
edema; glaucoma; headaches; hemorrhoids; joint inflammation; legs jerking at
night; enlarged prostate. Skin: brown spots, cellulite, excema, itching,
psoriasis, sagging, old surgical scars, spider veins.
Bioavailability
PCO is water-soluble and very well absorbed. Within 60 minutes of ingestion it
is absorbed and spread throughout the body. After seven hours, half of the
original dose is still found to be functionally available within the body. In
contrast with most antioxidants, PCO can cross the blood-brain barrier and as a
result protect the brain from the effects of free radical damage linked with
aging.