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What is Pleth Machine?

Pleth Machine is a software suite for the analysis of long-term plethysmography experiments.  It can perform chronological analysis of up to 10 parameters on 4 series of up to 190 samples each. 

It can filter samples using any one of 7 different unique or group identifiers, such as sex, species, drug intervention and dose and date of experiment.

If every sample has around 10 timepoints, that's a total database size of over 129,000 entries!

Do you really want to plot that data by hand?

Archives

July 8th 2006 -The Independence Horse Show was a great success.  Samurai Scientific's software helped reduce the enrollment time by 66% compared to the prior year, and provided riders and volunteers with schedules for the events of the day.

June 28th 2006 - Samurai Scientific volunteers its services to design a entrant-registration database package for the Independence Horse Show - a charitable event for disabled children in Upstate New York.  The show is scheduled for July 8th and the software will organize the riders' information and create reports for each rider and the class judges.

March 17th 2006 - Pleth Machine receives an upgrade in the form of version 0.81b, adding the capacity to analyze percentage changes in baseline parameters such as weight.  This upgrade was added to Pleth Machine rather than wait for Aphevio, to get the capability out to our users, and as an illustration of how flexible Pleth Machine can be.  The upgrade, once requested, took just a day to integrate into the existing code of Pleth Machine.  In addition, the customer who requested the analysis received their results back by return email the next day!

February 19th 2006 - Data analyzed using Pleth Machine has been accepted for publication!  To further validate the analysis presented at the Pediatric Academic Societies and the Infectious Diseases Society of America meetings in Washington and San Francisco last year, some of the same data and additional analyses have been published in - Bonville CA, Bennett, NJ, Koehnlein M, Haines DM, Ellis JA, DelVecchio AM, Rosenberg HF, Domachowske JB. 2006. "Respiratory dysfunction and proinflammatory chemokines in the pneumonia virus of mice (PVM) model of viral bronchiolitis". Virology 2006 May 25;349(1):87-95.

July 7th 2005 - Samurai Scientific signs a partnership agreement with International Business Machines Corp (IBM) to become an official partner of the World Community Grid.  Samurai is extremely proud to be able to offer official support to this philanthropic project.

June 8th 2005 - We go live with the new incarnation of the Samurai Scientific website.

May 19th 2005 - The latest evolution of the Numalisis algorithm is now in development, called Aphevio.  Aphevio builds upon the rapid, comprehensive analysis routines of Pleth Machine but puts control of analysis definitions firmly in the hands of the user.  Watch this space for updates over the next few months!

May 19th 2005 - The Pediatric Academic Societies meeting in Washington was a resounding success, with plenty of interest in the Pleth Machine software!  We look forward to building on the new relationships that were initiated at the meeting.  We'll be posting more news on developments as they happen.

May 4th 2005 - The HelpFile has been updated to reflect new troubleshooting issues and correct some typos.  Download it from the Downloads section!

April 20th 2005 - Better late than never...!  The demo version of Pleth Machine is now available.  We've been taking the time to develop a short tutorial to use with the demo version, so we think the delay is justified.

April 18th 2005 - Pleth Machine V0.8b is now complete and in the process of being packaged as a ZIP file along with the documentation.  We are also, for the first time, offering a downloadable demo of Pleth Machine which will be posted in the Downloads section.  The demo contains a mock database for analysis but limits the addition of new data, and saving and printing is disabled.

April 13th 2005 - The finishing touches are currently being made to version 0.8b!  User feedback from 0.7b highlighted the fact that the graphical display of chronological data was in a single format (a scatter plot with a 3-way moving average superimposed) which sometimes required post-analysis alteration for data presentation.  V0.8b adds new controls to alter the format in which the data is displayed, and also uses more open-ended code that will enable later versions of the Pleth Machine to use many more timepoints in the analyses.  After fine tuning the new graphical display and bug-testing, version 0.8b will be complete, and a demonstration version will be available for download shortly thereafter.

April 8th 2005 - Samurai Scientific goes online!  Welcome to our new website: please explore and drop us a line.  We are actively seeking feedback and advice from potential clients involved in scientific research, in particular those who work with large complex datasets of samples.  Although we are initially targeting the field of plethysmography, the underlying code of the Pleth Machine suite is customizable for any sample set involving chronological samples of hundreds of individuals.  Feel free to assist us by downloading our questionnaire (it's only 11 questions!)

March 15th 2005 - Samurai Scientific founded to develop and market the Pleth Machine software suite.  Samurai Scientific establishes its sole ownership of the copyright to Pleth Machine.

February 4th 2005 - Pleth Machine Version 0.7b finished.  Analyses performed with the software have already been submitted for publication and included in poster presentations.  Version 0.7b can analyze 4 different series of up to 190 samples and plot data for 10 different experimental parameters over a month-long period.  Kaplan-Meier survival curves are the newest feature, and include 95% confidence intervals and the point of 50% losses.

August 1st 2004 - Development of Pleth Machine begins, a new data analysis software suite initially aimed at the analysis of plethysmography data.  The aim is to create a program capable of analyzing multiple parameters for hundreds of individuals over time, perform correlational analysis between parameters, and additional complex analyses of the data as opportunities are seen.

Downloadable Demo version of Pleth Machine now released!

Check out the downloads section....

Questionnaire for researchers (Word document)